Cellulose Acetate Membranes

Membranes for use in clinical chemistry, haematology and routine analysis:

Cellulose Acetate Membranes

Pure cellulose acetate

Supported Cellulose Acetate Membranes

Cellulose membrane cast onto Mylar backing

Principle

All membranes are supplied in pre-cut dimensions for immediate use in all electrophoresis apparatus. Apacor supplies a comprehensive range of ancillary products including cells, buffers, reagents and stains which have been optimised for use with the Apacor membranes.

The electrophoretic separation and detection of haemoglobins is a principal application for the Apacor Cellulose Acetate and Supported Cellulose Acetate Membranes. The membranes provide unrivalled clarity for the diagnosis of haemoglobinopathies including Sickle Cell Diseases.

Haemoglobinopathies occur when production of normal adult haemoglobin is suppressed and replaced by one or more variants, or normal haemoglobins are produced in abnormal proportions. Screening can highlight these abnormalities before the onset of symptoms, allowing better patient management and counselling.

Electrophoresis exploits the negative charge which haemoglobin will adopt under alkaline conditions; since each haemoglobin variant carries a different net charge, they will all migrate at different speeds. Following electrophoretic migration these fractions are visualised by staining and classified by comparison with known standards.

Health and Safety Benefits

• Comprehensive range of membranes
• Clinical and routine analysis
• All reagents and hardware supplied
• Can be used in all machines

Performance Benefits:

• High sensitivity
• Easy to handle
• Clear resolution
• Reproducible results